The female reproductive system is intricate and vital, necessitating regular gynecological consultations for comprehensive evaluations. It is recommended to undergo gynecological examinations at least once a year, regardless of complaints, to detect and prevent potential issues early on. Early diagnosis through regular examinations is key to preventing the progression of reproductive system problems. The adage “prevention is better than cure” holds particularly true in matters of reproductive health.
The ROSI Technique: A Comprehensive Overview
Before delving into ROSI, understanding sperm production stages is crucial. The complex process spans approximately 90 days, progressing from spermatogonia to spermatocytes, spermatids, and finally, mature spermatozoa. Azoospermic men lack mature sperm cells in their semen, necessitating the examination of spermatid precursors, typically considered incapable of fertilizing eggs.
The ROSI technique, utilizing advanced technologies, makes fertilization possible with round and elongated spermatids.
In contrast to classical in vitro fertilization (IVF), where mature sperm cells are collected from ejaculate, ROSI deals with the absence of mature sperm. Instead, round cells extracted through testicular biopsy are introduced into oocytes, allowing for fertilization. The implementation of ROSI, initiated in February 2019 with equipment from Japan, has provided a promising solution for cases where mature sperm is absent.
The New Generation of ROSI in Seven Steps:
- Evaluation of both partners’ situations.
- Hormone analysis and 6-8 weeks of treatment for the male partner.
- Initiation of egg augmentation for the female partner on the 2nd or 3rd day of menstruation.
- Simultaneous collection of mature eggs and sperm cell search through testicular biopsy (TESE).
- Fertilization of eggs with mature sperm cells or, in the absence of mature cells, fertilization with round or long sperm cells.
- Stimulation of fertilized eggs through special electrical activation.
- Transfer of obtained embryos.
Understanding Azoospermia and the ROSI Technique
Azoospermia, the absence of live sperm cells in ejaculate despite the presence of semen, affects approximately one percent of men in the population. Thirty percent of men seeking infertility consultation also face azoospermia. Traditional treatments include surgical procedures or hormonal interventions; however, not all cases respond positively. For individuals hesitant about sperm donation, the Round Spermatid Injection (ROSI) technique serves as a viable alternative.
ROSI: A Game-Changing Alternative for Azoospermia Cases
Azoospermia, indicating the absence of sperm in ejaculate, can be challenging to treat with traditional methods. Surgical techniques or hormonal treatments may not yield positive results in all cases. Enter ROSI, a revolutionary technique offering an alternative for individuals unwilling to consider sperm donation. ROSI utilizes spermatids, the precursors to spermatozoa, extracted through testicular surgery, providing a promising avenue for fertilization.
As Stem&Gene ART Clinic we present a comprehensive narrative on the transformative impact of Round Spermatid Injection (ROSI) in addressing male infertility and the significance of regular gynecological examinations for overall reproductive health.
